SCHEMBL20544211

SCHEMBL20544211

CC(=O)CC(SCC(=O)O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.60
ALDH1A1 P00352 5/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
ALKBH5 Q6P6C2 1/20 0.45
SLC6A3 Q01959 1/20 0.42
KDM4E B2RXH2 2/20 0.41
FFAR1 O14842 1/20 0.40
GABBR2 O75899 1/20 0.40
GABBR1 Q9UBS5 1/20 0.40
CDC25B P30305 2/20 0.39
KMT2A Q03164 2/20 0.38
CYSLTR2 Q9NS75 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38
S100A4 P26447 1/20 0.38
ALB P02768 1/20 0.38
CYP2C9 P11712 1/20 0.38
PCSK7 Q16549 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23531383 0.86 PDPK1 (0.44) PDPK1ALDH1A1MAPTLMNASLC6A3
SCHEMBL8895206 0.84 PDPK1 (0.43) PDPK1ALDH1A1MAPTLMNASLC6A3
SCHEMBL15265480 0.84 ALDH1A1 (0.47) PDPK1ALDH1A1SLC6A3FFAR1KMT2A
SCHEMBL10795017 0.76 PDPK1 (0.49) PDPK1ALDH1A1MAPTGAAALKBH5
SCHEMBL28990121 0.75 PDPK1 (1.00) PDPK1ALDH1A1MAPTLMNAGAA
SCHEMBL14580238 0.75 PDPK1 (0.75) PDPK1ALDH1A1MAPTLMNAGAA
SCHEMBL2550325 0.75 PDPK1 (1.00) PDPK1ALDH1A1MAPTLMNAGAA
SCHEMBL12285363 0.75 L3MBTL1 (0.64) PDPK1ALDH1A1MAPTLMNAGAA
SCHEMBL20544320 0.75 KDM4E (0.40) ALDH1A1MAPTLMNAKDM4ECDC25B
SCHEMBL20544118 0.75 PDPK1 (0.51) PDPK1ALDH1A1MAPTLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828240-B1 COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE PERFUMING MOLECULES FIRMENICH & CIE (CH) 2018-10-31 EP claimed