SCHEMBL20544320

SCHEMBL20544320

CC(=O)CC(SC(C)C(=O)O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
APAF1 O14727 1/20 0.39
MAP2K7 O14733 1/20 0.39
ELANE P08246 1/20 0.39
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39
CYP2D6 P10635 1/20 0.38
SRC P12931 1/20 0.38
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 2/20 0.37
ALB P02768 1/20 0.37
CYP2C9 P11712 1/20 0.37
PCSK7 Q16549 1/20 0.37
HSD17B10 Q99714 1/20 0.37
VKORC1 Q9BQB6 1/20 0.37
MEN1 O00255 1/20 0.37
MTNR1A P48039 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20544076 0.78 APAF1 (0.37) MAPTAPAF1CYP2D6SRCLMNA
SCHEMBL23531383 0.77 PDPK1 (0.44) KDM4EALDH1A1MAPTCYP2D6SRC
SCHEMBL7254921 0.76 NPSR1 (0.50) KDM4EALDH1A1MAPTMAPK1KMT2A
SCHEMBL8895206 0.76 PDPK1 (0.43) KDM4EALDH1A1MAPTLMNAKMT2A
SCHEMBL6186896 0.75 PDPK1 (0.47) KDM4EALDH1A1MAPTCYP2D6LMNA
SCHEMBL20544211 0.75 PDPK1 (0.60) KDM4EALDH1A1MAPTCDC25BLMNA
SCHEMBL8675122 0.74 CYP2D6 (0.46) KDM4EALDH1A1MAPTAPAF1MAP2K7
SCHEMBL1149769 0.72 FFAR1 (0.53) KDM4EALDH1A1MAPT
SCHEMBL11484603 0.72 FFAR1 (0.53) KDM4EALDH1A1MAPT
SCHEMBL1149358 0.72 FFAR1 (0.53) KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828240-B1 COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE PERFUMING MOLECULES FIRMENICH & CIE (CH) 2018-10-31 EP claimed