SCHEMBL20544701

SCHEMBL20544701

[CH2]COC(=O)NCCC[Si](OC)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.43
EPHX1 P07099 1/20 0.39
GLA P06280 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13978949 0.85 ACHE (0.60) ACHEEPHX1
SCHEMBL9452192 0.84 ACHE (0.55) ACHEEPHX1
SCHEMBL141826 0.84 ACHE (0.48) ACHEEPHX1GLAKMT2A
SCHEMBL20544859 0.83 ACHE (0.44) ACHEEPHX1
SCHEMBL467687 0.83 EPHX1 (0.55) ACHEEPHX1KMT2A
SCHEMBL28636268 0.82 ACHE (0.54) ACHEEPHX1
SCHEMBL28635662 0.82 ACHE (0.45) ACHEKMT2A
SCHEMBL7090002 0.81 BRD4 (0.42) ACHEEPHX1
SCHEMBL28925138 0.81 ACHE (0.47) ACHE
SCHEMBL28299554 0.81 EPHX1 (0.53) ACHEEPHX1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3404055-B1 COMPOSITION, FILM, GLASS ARTICLE, COMPOUND, HIGH PURITY COMPOSITION, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING FILM FUJIFILM CORP (JP) 2023-08-16 EP disclosed
US-11364710-B2 Composition, film, glass article, compound, high purity composition, method for producing compound, and method for producing film FUJIFILM CORPORATION (JP) 2022-06-21 US disclosed
CN-108463487-B Composition, film, glass product, compound, high-purity composition, method for producing compound, and method for producing film 富士胶片株式会社 2020-11-27 CN disclosed
EP-3404055-A1 COMPOSITION, FILM, GLASS ARTICLE, COMPOUND, HIGH PURITY COMPOSITION, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING FILM FUJIFILM Corporation (JP) 2018-11-21 EP disclosed
US-20180311936-A1 COMPOSITION, FILM, GLASS ARTICLE, COMPOUND, HIGH PURITY COMPOSITION, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING FILM FUJIFILM CORPORATION (JP) 2018-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11364710-B2 Composition, film, glass article, compound, high purity composition, method for producing compound, and method for producing film SOST, VCL, CCNO ACHE 1462/4885EPHX1 1556/4885GLA 359/4885
US-20180311936-A1 COMPOSITION, FILM, GLASS ARTICLE, COMPOUND, HIGH PURITY COMPOSITION, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING FILM SOST, VCL, CCNO ACHE 1462/4885EPHX1 1556/4885GLA 359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.