Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 9/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19753736 | 0.87 | ACHE (0.42) | ACHEEPHX1 | |
| SCHEMBL35366 | 0.84 | ACHE (0.38) | BRD4ACHEHRH4HRH3ERN1 | |
| SCHEMBL20544701 | 0.81 | ACHE (0.43) | ACHEEPHX1 | |
| SCHEMBL13978949 | 0.81 | ACHE (0.60) | ACHEHRH3EPHX1 | |
| SCHEMBL3676772 | 0.81 | TGM2 (0.46) | ACHEERN1EPHX1TSHR | |
| SCHEMBL16920092 | 0.80 | ACHE (0.47) | ACHEHRH4HRH3TSHRALDH1A1 | |
| SCHEMBL19753742 | 0.80 | EPHX2 (0.45) | ACHEEPHX1 | |
| SCHEMBL20608972 | 0.80 | EPHX1 (0.38) | ACHEEPHX1TSHR | |
| SCHEMBL141826 | 0.80 | ACHE (0.48) | ACHEEPHX1 | |
| SCHEMBL9452192 | 0.80 | ACHE (0.55) | ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991698-B1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-10-24 | — | — | EP | disclosed |
| US-6515043-B2 | Surface treatment of filler | CROMPTON CORPORATION | 2003-02-04 | — | — | US | disclosed |
| US-6395856-B1 | CURABLE POLYSILOXANES FOR PROTECTIVE COATINGS FOR WIRES | CROMPTON CORPORATION | 2002-05-28 | — | — | US | disclosed |
| US-20010021761-A1 | Silicone oligomers with heigher alkoxy groups | MOMENTIVE PERFORMANCE MATERIALS INC. | 2001-09-13 | — | — | US | disclosed |
| US-6207783-B1 | UNDERGROUND INSULATION | CROMPTON CORPORATION | 2001-03-27 | — | — | US | disclosed |
| EP-0991698-A1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | CK WITCO CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999054386-A1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | WITCO CORPORATION (US) | 1999-10-28 | — | — | WO | disclosed |