SCHEMBL20544792

SCHEMBL20544792

NCCCCC1Oc2ccccc2O1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.43
MAOA P21397 1/20 0.39
HRH1 P35367 3/20 0.35
HTR2A P28223 2/20 0.35
HTT P42858 1/20 0.34
F10 P00742 1/20 0.33
PRSS1 P07477 1/20 0.33
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL407486 0.85 CA2 (0.47) CA2HRH1HTR2AHTT
SCHEMBL15111194 0.78 GRM2 (0.45)
SCHEMBL9618689 0.77 HPGD (0.43) CA2
SCHEMBL3636160 0.77 CA2 (0.44) CA2HTT
SCHEMBL437597 0.75 CA2 (0.50) CA2HTR2A
SCHEMBL17592746 0.75 L3MBTL1 (0.44) CA2HRH1HTR2A
Butylamine SCHEMBL29138994 0.75 CA2 (0.40) CA2
SCHEMBL25175948 0.73 CA2 (0.39) CA2MAOA
Hydrochloric Acid SCHEMBL25190303 0.73 MEN1 (0.43) CA2HRH1HTR2A
SCHEMBL28916486 0.72 CA2 (0.37) CA2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4079311-B1 NMN AND DERIVATIVES FOR USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM NUVAMID SA (CH) 2025-10-01 EP disclosed
US-20240417421-A1 NMN And Derivatives For Its Use In The Treatment Of Depression And/Or Anxiety In Patients Having A Form Of Parkinsonism NUVAMID SA (CH) 2024-12-19 US disclosed
US-20240116971-A1 NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM NUVAMID SA (CH) 2024-04-11 US disclosed
WO-2023141595-A2 FUNCTIONALIZED ALKYLAMINES TERRAN BIOSCIENCES, INC. (US) 2023-07-27 WO disclosed
WO-2022223612-A1 NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF ALPHA-SYNUCLEINOPATHIES NUVAMID SA (CH) 2022-10-27 WO disclosed
WO-2022223613-A1 NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM NUVAMID SA (CH) 2022-10-27 WO disclosed
EP-4079311-A1 NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM Nuvamid SA (CH) 2022-10-26 EP disclosed
EP-4079310-A1 NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF ALPHA-SYNUCLEINOPATHIES Nuvamid SA (CH) 2022-10-26 EP disclosed
US-11383084-B2 Treatment of dermatological conditions via neuromodulation PALO ALTO INVESTORS (US) 2022-07-12 US disclosed
US-20180311499-A1 Treatment of Dermatological Conditions via Neuromodulation PALO ALTO INVESTORS 2018-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116971-A1 NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM SNCA, NLN, PARK7 CA2 4064/4885MAOA 47/4885HRH1 1900/4885
US-20240417421-A1 NMN And Derivatives For Its Use In The Treatment Of Depression And/Or Anxiety In Patients Having A Form Of Parkinsonism SNCA, NLN, PARK7 CA2 4633/4885MAOA 64/4885HRH1 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.