SCHEMBL20545202

SCHEMBL20545202

CCCCCCCCCCCCCC(C(=O)OCCCC)C(O)(CCCCCCCCCCCCC)C(=O)OCCCC.[SnH2]

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.49
LMNA P02545 1/20 0.49
HSPD1 P10809 1/20 0.41
BLM P54132 1/20 0.41
HSPE1 P61604 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HPGD P15428 1/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NAAA Q02083 1/20 0.37
ZDHHC7 Q9NXF8 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 2/20 0.36
ATM Q13315 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EPHX1 P07099 1/20 0.35
SMPD1 P17405 2/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20544767 0.91 LMNA (0.42) USP2LMNAHSPD1BLMHSPE1
SCHEMBL9845289 0.84 USP2 (0.61) USP2LMNAHSPD1BLMHSPE1
SCHEMBL8147278 0.84 USP2 (0.61) USP2LMNAHSPD1BLMHSPE1
SCHEMBL3257863 0.83 USP2 (0.59) USP2LMNAHSPD1BLMHSPE1
SCHEMBL1072222 0.82 USP2 (0.61) USP2LMNAHSPD1BLMHSPE1
SCHEMBL3834335 0.82 LMNA (0.42) USP2LMNAHSPD1BLMHSPE1
SCHEMBL5166269 0.82 USP2 (0.61) USP2LMNAHSPD1BLMHSPE1
SCHEMBL1218317 0.82 HSPD1 (0.57) USP2LMNAHSPD1BLMHSPE1
SCHEMBL28120373 0.82 USP2 (0.61) USP2LMNAHSPD1BLMHSPE1
SCHEMBL7555878 0.79 NAAA (0.42) USP2LMNAHSPD1BLMHSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398986-A1 MODIFIED SILICONE RESIN FOAM Kaneka Corporation (JP) 2018-11-07 EP disclosed
US-20180312653-A1 MODIFIED SILICONE RESIN FOAM KANEKA CORPORATION (JP) 2018-11-01 US disclosed