Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 11/20 | 1.00 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | HTR2B | P41595 | 4/20 | 0.60 |
| ▸ | HTR1D | P28221 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR1E | P28566 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20546705 | 0.82 | HTR7 (1.00) | HTR7HTR2CHTR2BHTR1DHTR2A | |
| SCHEMBL20547198 | 0.82 | HTR7 (1.00) | HTR7HTR2CHTR2BHTR1DHTR2A | |
| SCHEMBL20546703 | 0.78 | HTR7 (1.00) | HTR7HTR2CHTR2BHTR1DHTR2A | |
| SCHEMBL2074336 | 0.75 | HTR7 (1.00) | HTR7HTR2CHTR2BHTR1DHTR2A | |
| SCHEMBL20547146 | 0.74 | HTR7 (1.00) | HTR7HTR2CHTR2BHTR1DHTR2A | |
| SCHEMBL20547195 | 0.73 | HTR7 (1.00) | HTR7HTR2CHTR2BHTR1DHTR2A | |
| SCHEMBL10816303 | 0.72 | HTR7 (0.81) | HTR7HTR2CHTR2BHTR1DHTR2A | |
| SCHEMBL24587141 | 0.69 | HTR7 (0.52) | HTR7MAPTHPGD | |
| SCHEMBL20546707 | 0.69 | HTR7 (1.00) | HTR7HTR2CHTR2BHTR1DHTR2A | |
| SCHEMBL2474118 | 0.69 | SOS1 (0.57) | HTR7HTR2CHTR2BHTR1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560927-A1 | AZEPINE DERIVATIVE ACTING AS 5-HT7 RECEPTOR MODULATOR | Korea Institute of Science and Technology (KR) | 2019-10-30 | — | — | EP | claimed |
| US-10435408-B2 | Azepine derivatives as 5-HT7 receptor modulators | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-10-08 | — | — | US | claimed |
| US-20180312509-A1 | AZEPINE DERIVATIVES AS 5-HT7 RECEPTOR MODULATORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-11-01 | — | — | US | claimed |
| EP-3560927-B1 | AZEPINE DERIVATIVES ACTING AS 5-HT7 RECEPTOR MODULATORS | KOREA INST SCI & TECH (KR) | 2023-04-19 | — | — | EP | disclosed |
| EP-3560927-A1 | AZEPINE DERIVATIVE ACTING AS 5-HT7 RECEPTOR MODULATOR | Korea Institute of Science and Technology (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-10435408-B2 | Azepine derivatives as 5-HT7 receptor modulators | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-10-08 | — | — | US | disclosed |
| US-20180312509-A1 | AZEPINE DERIVATIVES AS 5-HT7 RECEPTOR MODULATORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312509-A1 | AZEPINE DERIVATIVES AS 5-HT7 RECEPTOR MODULATORS | HTR7, HTR5A, HTR3A | HTR7 1/4885HTR2C 10/4885HTR2B 9/4885 |
| US-10435408-B2 | Azepine derivatives as 5-HT7 receptor modulators | HTR7, HTR5A, HTR3A | HTR7 1/4885HTR2C 10/4885HTR2B 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.