Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | FURIN | P09958 | 9/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | NPY1R | P25929 | 4/20 | 0.44 |
| ▸ | NPY4R | P50391 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548854 | 0.93 | NPY4R (0.49) | SIRT5SIRT2FURINNPY5RNPY1R | |
| SCHEMBL29612115 | 0.93 | NPY4R (0.49) | SIRT5SIRT2FURINNPY5RNPY1R | |
| SCHEMBL31521783 | 0.93 | NPY4R (0.49) | SIRT5SIRT2FURINNPY5RNPY1R | |
| SCHEMBL20548859 | 0.93 | NPY4R (0.49) | SIRT5SIRT2FURINNPY5RNPY1R | |
| SCHEMBL30491818 | 0.93 | NPY4R (0.49) | SIRT5SIRT2FURINNPY5RNPY1R | |
| SCHEMBL31521781 | 0.93 | NPY4R (0.49) | SIRT5SIRT2FURINNPY5RNPY1R | |
| SCHEMBL28310809 | 0.87 | NPY4R (0.52) | SIRT5FURINNPY5RNPY1RNPY4R | |
| SCHEMBL12035314 | 0.86 | NPY4R (0.48) | SIRT5SIRT2NPY5RNPY1RNPY4R | |
| SCHEMBL12035276 | 0.86 | SIRT5 (0.44) | SIRT5NPY5RNPY1RNPY4R | |
| SCHEMBL31521782 | 0.86 | NPY4R (0.44) | SIRT5SIRT2NPY5RNPY1RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4071135-B1 | ETELCALCETIDE INTERMEDIATE AND METHOD FOR SYNTHESIZING ETELCALCETIDE | ASYMCHEM LAB TIANJIN CO LTD (CN) | 2024-11-27 | — | — | EP | disclosed |
| US-20230021514-A1 | Etelcalcetide intermediate and method for synthesizing etelcalcetide | ASYMCHEM LABORATORIES (TIANJIN) CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
| EP-4071135-A1 | ETELCALCETIDE INTERMEDIATE AND METHOD FOR SYNTHESIZING ETELCALCETIDE | Asymchem Laboratories (Tianjin) Co., Ltd. (CN) | 2022-10-12 | — | — | EP | disclosed |
| WO-2021109297-A1 | ETELCALCETIDE INTERMEDIATE AND METHOD FOR SYNTHESIZING ETELCALCETIDE | 凯莱英医药集团（天津）股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| EP-3398957-B1 | METHOD FOR SYNTHESIZING ETELCALCETIDE | HYBIO PHARMACEUTICAL CO LTD (CN) | 2020-09-02 | — | — | EP | disclosed |
| US-10647742-B2 | Method for synthesizing etelcalcetide | Hybio Pharmaceutical Co., Ltd. (CN) | 2020-05-12 | — | — | US | disclosed |
| CN-110668984-B | Etecatide intermediate and synthetic method of Etecatide | 凯莱英医药集团（天津）股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-110668984-A | Etecatide intermediate and synthetic method of Etecatide | 凯莱英医药集团（天津）股份有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-20190010185-A1 | METHOD FOR SYNTHESIZING ETELCALCETIDE | Hybio Pharmaceutical Co., Ltd. (CN) | 2019-01-10 | — | — | US | disclosed |
| EP-3398957-A1 | METHOD FOR SYNTHESIZING ETELCALCETIDE | Hybio Pharmaceutical Co., Ltd (CN) | 2018-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647742-B2 | Method for synthesizing etelcalcetide | PTMS, PTH1R, ECE2 | SIRT5 3212/4885SIRT2 3438/4885FURIN 75/4885 |
| US-20190010185-A1 | METHOD FOR SYNTHESIZING ETELCALCETIDE | PTMS, PTH1R, ECE2 | SIRT5 3212/4885SIRT2 3438/4885FURIN 75/4885 |
| US-20230021514-A1 | Etelcalcetide intermediate and method for synthesizing etelcalcetide | PTMS, CTSS, SOST | SIRT5 3951/4885SIRT2 4286/4885FURIN 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.