Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 5/20 | 0.47 |
| ▸ | CDK9 | P50750 | 5/20 | 0.47 |
| ▸ | CDK7 | P50613 | 4/20 | 0.47 |
| ▸ | CCNH | P51946 | 4/20 | 0.47 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.47 |
| ▸ | CDK2 | P24941 | 7/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.39 |
| ▸ | JUN | P05412 | 5/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20549338 | 0.90 | HTR6 (0.40) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL21027469 | 0.86 | CCNT1 (0.52) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL20549548 | 0.85 | CDK7 (0.46) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL17688395 | 0.85 | CDK7 (0.51) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL19024518 | 0.85 | CDK7 (0.51) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL17150473 | 0.85 | CDK7 (0.51) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL20536159 | 0.85 | CDK7 (0.51) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL17150411 | 0.84 | CDK7 (0.51) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL16665199 | 0.82 | CDK7 (0.58) | CCNT1CDK9CDK7CCNHMNAT1 | |
| SCHEMBL16654932 | 0.82 | CDK7 (0.48) | CCNT1CDK9CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180319772-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2018-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319772-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CCNT1 34/4885CDK9 3/4885CDK7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.