Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.58 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409544 | 0.89 | AKR1B10 (0.58) | PTGDR2PTGDRBAZ2BADRA2AHTR2A | |
| SCHEMBL13142326 | 0.80 | HRH1 (0.74) | PTGDR2PTGDRADRA2AHTR2AHTR2C | |
| SCHEMBL3425662 | 0.75 | HRH1 (0.75) | PTGDR2PTGDRADRA2AHTR2AHTR2C | |
| SCHEMBL3087175 | 0.73 | PTGDR2 (1.00) | PTGDR2PTGDRBAZ2B | |
| SCHEMBL410245 | 0.72 | MAPT (0.65) | ADRA2AHTR2AHTR2CHTR7ADRA1A | |
| SCHEMBL3083804 | 0.72 | PTGDR2 (0.68) | PTGDR2PTGDRBAZ2BAKR1B10AKR1B1 | |
| SCHEMBL2243442 | 0.71 | PTGDR2 (0.59) | PTGDR2PTGDRHDAC1HDAC6 | |
| SCHEMBL3316702 | 0.71 | PTGDR2 (0.69) | PTGDR2PTGDRBAZ2BADRA2AHTR2A | |
| SCHEMBL3024366 | 0.71 | HTR6 (0.73) | PTGDR2PTGDRBAZ2BADRA2AHTR2A | |
| SCHEMBL3024370 | 0.71 | HTR6 (0.73) | PTGDR2PTGDRBAZ2BADRA2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180318255-A1 | Pro-Neurogenic Compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2018-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180318255-A1 | Pro-Neurogenic Compounds | BDNF, GAP43, DCX | PTGDR2 566/4885PTGDR 308/4885BAZ2B 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.