SCHEMBL20550883

SCHEMBL20550883

O=C(Nc1nccc(C=NC2CCCC2)n1)OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
TSHR P16473 2/20 0.41
FSHR P23945 1/20 0.41
KDM1A O60341 2/20 0.40
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
ALDH1A1 P00352 2/20 0.40
RCOR1 Q9UKL0 1/20 0.40
GRM4 Q14833 1/20 0.39
GRIN2B Q13224 1/20 0.39
EPHX1 P07099 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
GAA P10253 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29842127 0.99 POLB (0.42) POLBTSHRFSHRKDM1AMAOA
SCHEMBL30035439 0.99 POLB (0.42) POLBTSHRFSHRKDM1AMAOA
SCHEMBL30033692 0.99 POLB (0.42) POLBTSHRFSHRKDM1AMAOA
SCHEMBL20550534 0.98 POLB (0.43) POLBTSHRFSHRKDM1AMAOA
SCHEMBL20550940 0.96 POLB (0.44) POLBTSHRFSHRKDM1AMAOA
SCHEMBL20550902 0.90 POLB (0.43) POLBTSHRFSHRKDM1AMAOA
SCHEMBL29841789 0.89 TSHR (0.40) POLBTSHRFSHRKDM1AMAOA
SCHEMBL30944258 0.89 TGM2 (0.50) MAOBMAPTTGM2
SCHEMBL20551152 0.86 POLB (0.41) POLBTSHRFSHRKDM1AMAOA
SCHEMBL20551136 0.85 TSHR (0.41) POLBTSHRFSHRKDM1AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3619204-B1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES TIANLI BIOTECH PTY LTD (AU) 2025-10-01 EP disclosed
US-20220380343-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES TIANLI BIOTECH PTY LTD (AU) 2022-12-01 US disclosed
US-20200079757-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES THE UNIVERSITY OF MELBOURNE (AU) 2020-03-12 US disclosed
EP-3619204-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES The University of Melbourne (AU) 2020-03-11 EP disclosed
WO-2018201192-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES THE UNIVERSITY OF MELBOURNE (AU) 2018-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220380343-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES LTC4S, LTB4R2, LTB4R POLB 1332/4885TSHR 4372/4885FSHR 4156/4885
US-20200079757-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES LTC4S, LTB4R2, LTB4R POLB 1332/4885TSHR 4372/4885FSHR 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.