SCHEMBL20556697

SCHEMBL20556697

CC(=O)N(C)c1cnn(C(=O)N2CCN(Cc3ccc(C(F)(F)F)cc3N3CCCC3)CC2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20556974 0.89 FAAH (0.58) FAAH
SCHEMBL21094508 0.87 — —
SCHEMBL20557016 0.86 — —
SCHEMBL17276468 0.86 FAAH (0.67) FAAH
SCHEMBL17276559 0.86 FAAH (0.67) FAAH
SCHEMBL20556711 0.85 MGLL (0.57) —
SCHEMBL20557033 0.84 FAAH (0.61) FAAH
SCHEMBL20503633 0.84 FAAH (0.71) FAAH
SCHEMBL20556769 0.84 — —
SCHEMBL17276776 0.84 FAAH (0.65) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323038-B2 Pyrazole compounds and methods of making and using same ABIDE THERAPEUTICS, INC. (US) 2019-06-18 — — US disclosed
US-10323038-B2 Pyrazole compounds and methods of making and using same ABIDE THERAPEUTICS, INC. (US) 2019-06-18 — — US disclosed
US-20180327416-A1 PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2018-11-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180327416-A1 PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME FAAH, FAAH2, MGLL FAAH 1/4885
US-10323038-B2 Pyrazole compounds and methods of making and using same FAAH, FAAH2, MGLL FAAH 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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