Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21094331 | 0.89 | FAAH (0.40) | MGLL | |
| SCHEMBL20556767 | 0.88 | — | — | |
| SCHEMBL20557042 | 0.83 | — | — | |
| SCHEMBL22350624 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1KDM4CTDP1MGLL | |
| SCHEMBL20503526 | 0.82 | MGLL (0.49) | KDM4EALDH1A1KDM4CTDP1MGLL | |
| SCHEMBL20557033 | 0.82 | FAAH (0.61) | MGLL | |
| SCHEMBL22350626 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1KDM4CTDP1MGLL | |
| SCHEMBL25829966 | 0.78 | FAAH (0.57) | MGLL | |
| SCHEMBL17276630 | 0.77 | KDM4E (0.49) | KDM4EPOLB | |
| SCHEMBL20557069 | 0.76 | FAAH (0.62) | ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323038-B2 | Pyrazole compounds and methods of making and using same | ABIDE THERAPEUTICS, INC. (US) | 2019-06-18 | — | — | US | disclosed |
| US-10323038-B2 | Pyrazole compounds and methods of making and using same | ABIDE THERAPEUTICS, INC. (US) | 2019-06-18 | — | — | US | disclosed |
| US-20180327416-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2018-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180327416-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | FAAH, FAAH2, MGLL | KDM4E 3429/4885ALDH1A1 1378/4885KDM4C 3436/4885 |
| US-10323038-B2 | Pyrazole compounds and methods of making and using same | FAAH, FAAH2, MGLL | KDM4E 3429/4885ALDH1A1 1378/4885KDM4C 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.