Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19716899 | 0.82 | HDAC1 (0.44) | KDM4ANQO2KCNA5NAMPTL3MBTL1 | |
| SCHEMBL21481996 | 0.82 | KDM4A (0.44) | KDM4ANQO2KCNA5NAMPTL3MBTL1 | |
| SCHEMBL18685355 | 0.82 | KDM4A (0.44) | KDM4ANQO2KCNA5NAMPTL3MBTL1 | |
| SCHEMBL30344301 | 0.81 | KCNA5 (0.47) | KDM4ANQO2KCNA5NAMPTL3MBTL1 | |
| SCHEMBL30454240 | 0.81 | KCNA5 (0.52) | KDM4ANQO2KCNA5NAMPTL3MBTL1 | |
| SCHEMBL6874894 | 0.81 | KCNA5 (0.52) | KDM4ANQO2KCNA5NAMPTL3MBTL1 | |
| SCHEMBL3124959 | 0.81 | ALDH1A1 (0.55) | KDM4AKCNA5L3MBTL1POLBGAA | |
| SCHEMBL13656743 | 0.79 | NQO2 (0.51) | KDM4ANQO2KCNA5NAMPTL3MBTL1 | |
| SCHEMBL23616924 | 0.79 | RPS6KA1 (0.52) | KDM4ANQO2KCNA5NAMPTL3MBTL1 | |
| SCHEMBL31706488 | 0.79 | KCNA5 (0.46) | KDM4ANQO2KCNA5NAMPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018205948-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-11-15 | — | — | WO | disclosed |