Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.94 |
| ▸ | MAPT | P10636 | 8/20 | 0.94 |
| ▸ | BACE1 | P56817 | 5/20 | 0.94 |
| ▸ | MMP9 | P14780 | 4/20 | 0.94 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.94 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.94 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.94 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.94 |
| ▸ | MAOA | P21397 | 2/20 | 0.94 |
| ▸ | MAOB | P27338 | 2/20 | 0.94 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.94 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.94 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.94 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.94 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.94 |
| ▸ | STAT3 | P40763 | 2/20 | 0.94 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Curcumin SCHEMBL2177792 | 1.00 | APP (0.94) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL2177794 | 1.00 | APP (0.94) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL40025 | 1.00 | APP (0.94) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL28213114 | 0.98 | APP (0.91) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL8336603 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL17629819 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL2804734 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL250984 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL6901740 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL8440 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103071117-A | Method for extracting curcuma oil and curcumine from rhizoma curcumae longae | SICHUAN HUIFENG BIOLOG TECHNOLOGY CO LTD | 2013-05-01 | — | — | CN | claimed |
| CN-118340908-A | ROS (reactive oxygen species) responsive material, and preparation method and application thereof | 广东亿超生物科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114557965-B | Phospholipid complex nanoparticle for improving stability and bioavailability of curcumin and preparation method thereof | 汕头大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-114196028-B | PAMAM-TPGS, and preparation method and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-113264817-B | Curcumin crystallization method and application thereof | 晨光生物科技集团股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-111110650-B | Preparation method of enzyme-sensitive amphiphilic polyester drug-loaded nanoparticles | 浙江工业大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-114557965-A | Phospholipid compound nanoparticles for improving curcumin stability and bioavailability and preparation method thereof | 汕头大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-114196028-A | PAMAM-TPGS, and preparation method and application thereof | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-113264817-A | Curcumin crystallization method and application thereof | 晨光生物科技集团股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-111587290-A | Beta-1, 3-1, 6-glucan powder, glucan-containing composition, method for producing beta-1, 3-1, 6-glucan powder, inclusion complex, method for producing inclusion complex, and method for recovering guest molecule | 三菱瓦斯化学株式会社 | 2020-08-25 | — | — | CN | disclosed |
| CN-107744514-B | Preparation method of star-shaped drug delivery nanoparticles with enzyme targeting property | 浙江工业大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-111110650-A | Preparation method of enzyme-sensitive amphiphilic polyester drug-loaded nanoparticles | 浙江工业大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-107243002-B | Preparation method of polytetracaprolactone-pentaerythritol administration nanoparticles | 浙江工业大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-107744503-B | Preparation method of enzyme-sensitive amphiphilic polyester MePEG-Peptide-PER-CL administration nanoparticle | 浙江工业大学 | 2020-04-07 | — | — | CN | disclosed |
| WO-2018211380-A1 | CURCUMINOID COMPOSITIONS | INVENTIA HEALTHCARE PRIVATE LIMITED (IN) | 2018-11-22 | — | — | WO | disclosed |
| CN-107744503-A | The preparation method of the amphipathic polyester MePEG Peptide PER CL administrations nanoparticle of enzyme sensitiveness | 浙江工业大学 | 2018-03-02 | — | — | CN | disclosed |
| CN-107744515-A | A kind of preparation method that nanoparticle is administered for controlled release characteristics of easing up with enzyme targeting | 浙江工业大学 | 2018-03-02 | — | — | CN | disclosed |
| CN-107744514-A | A kind of preparation method of the starlike administration nanoparticle with enzyme targeting | 浙江工业大学 | 2018-03-02 | — | — | CN | disclosed |
| CN-107243002-A | The preparation method of nanoparticle is administered in a kind of poly- four caprolactones pentaerythrite | 浙江工业大学 | 2017-10-13 | — | — | CN | disclosed |
| CN-103071117-A | Method for extracting curcuma oil and curcumine from rhizoma curcumae longae | SICHUAN HUIFENG BIOLOG TECHNOLOGY CO LTD | 2013-05-01 | — | — | CN | disclosed |