Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.94 |
| ▸ | MAPT | P10636 | 8/20 | 0.94 |
| ▸ | BACE1 | P56817 | 5/20 | 0.94 |
| ▸ | MMP9 | P14780 | 4/20 | 0.94 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.94 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.94 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.94 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.94 |
| ▸ | MAOA | P21397 | 2/20 | 0.94 |
| ▸ | MAOB | P27338 | 2/20 | 0.94 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.94 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.94 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.94 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.94 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.94 |
| ▸ | STAT3 | P40763 | 2/20 | 0.94 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Curcumin SCHEMBL2177794 | 1.00 | APP (0.94) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL20562725 | 1.00 | APP (0.94) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL2177792 | 1.00 | APP (0.94) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL28213114 | 0.98 | APP (0.91) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL8336603 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL17629819 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL17629818 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL250984 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL8440 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL6901740 | 0.97 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118340908-A | ROS (reactive oxygen species) responsive material, and preparation method and application thereof | 广东亿超生物科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-115581707-B | Preparation method of chitosan oligosaccharide-curcumin nanocomposite | 哈尔滨工业大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-115581707-A | Preparation method of chitosan oligosaccharide-curcumin nano complex | 哈尔滨工业大学 | 2023-01-10 | — | — | CN | disclosed |
| US-20220151945-A1 | SOLID LIPID NANOPARTICLES OF CURCUMIN | REGISTRAR, PANJAB UNIVERSITY CHANDIGARH (IN) | 2022-05-19 | — | — | US | disclosed |
| EP-3887350-A1 | SOLID LIPID NANOPARTICLES OF CURCUMIN | Registrar, Panjab University Chandigarh (IN) | 2021-10-06 | — | — | EP | disclosed |
| CN-112755007-A | Method for preparing drug-loaded biomembrane by using microbial fermentation product | 浙江摩达生物科技有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2020109989-A1 | SOLID LIPID NANOPARTICLES OF CURCUMIN | REGISTRAR, PANJAB UNIVERSITY CHANDIGARH (IN) | 2020-06-04 | — | — | WO | disclosed |
| WO-2011141721-A2 | COMPOSITIONS | IOTA NANOSOLUTIONS LIMITED (GB) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220151945-A1 | SOLID LIPID NANOPARTICLES OF CURCUMIN | PLIN1, LIPC, NPC1L1 | APP 2574/4885MAPT 1916/4885BACE1 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.