Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 8/20 | 0.54 |
| ▸ | HTR6 | P50406 | 5/20 | 0.52 |
| ▸ | FLT1 | P17948 | 4/20 | 0.51 |
| ▸ | FLT4 | P35916 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20561500 | 0.88 | L3MBTL1 (0.73) | L3MBTL1HTR6KDM4EUBE2NCYP19A1 | |
| SCHEMBL20564256 | 0.79 | HTR6 (0.72) | L3MBTL1HTR6CA12CA1CA2 | |
| SCHEMBL20562314 | 0.75 | HTR6 (0.54) | L3MBTL1HTR6KDM4EUBE2NCA12 | |
| SCHEMBL26911844 | 0.73 | L3MBTL1 (0.70) | L3MBTL1HTR6KDM4EUBE2NCYP19A1 | |
| SCHEMBL15805357 | 0.73 | PTPN11 (0.46) | L3MBTL1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15805355 | 0.73 | PTPN11 (0.48) | L3MBTL1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15805344 | 0.72 | PTPN11 (0.45) | L3MBTL1KDRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7549872 | 0.71 | KDR (0.81) | KDRFLT1FLT4CYP2A6 | |
| SCHEMBL28984412 | 0.71 | L3MBTL1 (0.77) | L3MBTL1HTR6KDM4EUBE2NCA12 | |
| SCHEMBL25422336 | 0.70 | HTR6 (0.61) | L3MBTL1HTR6KDM4EUBE2NCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |