Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357763 | 0.93 | HTR2A (0.41) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL320554 | 0.93 | HTR2A (0.41) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL31318310 | 0.71 | ALDH1A1 (0.33) | CYP3A4HSD17B10 | |
| Ethylene SCHEMBL61250 | 0.71 | HTR2A (0.36) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL186865 | 0.70 | HTR2A (0.41) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL186866 | 0.70 | HTR2A (0.41) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL29531714 | 0.70 | HTR2A (0.41) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL6763868 | 0.70 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL2136144 | 0.70 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL3685967 | 0.70 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11203609-B2 | Metal complexes | UNIVATION TECHNOLOGIES, LLC (US) | 2021-12-21 | — | — | US | disclosed |
| EP-3625239-B1 | A HAFNIUM COMPLEX; A SUPPORTED HAFNIUM COMPLEX; METHODS OF FORMING A POLYMER USING SUCH COMPLEXES | UNIVATION TECH LLC (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20200190128-A1 | METAL COMPLEXES | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-18 | — | — | US | disclosed |
| EP-3625239-A1 | A HAFNIUM COMPLEX; A SUPPORTED HAFNIUM COMPLEX; METHODS OF FORMING A POLYMER USING SUCH COMPLEXES | Univation Technologies, LLC (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018213395-A1 | A HAFNIUM COMPLEX; A SUPPORTED HAFNIUM COMPLEX; METHODS OF FORMING A POLYMER USING SUCH COMPLEXES | UNIVATION TECHNOLOGIES, LLC (US) | 2018-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11203609-B2 | Metal complexes | DNMT1, AP1M1, DNMT3A | HTR2A 3287/4885HTR6 2872/4885KDM4E 943/4885 |
| US-20200190128-A1 | METAL COMPLEXES | DNMT1, AP1M1, DNMT3A | HTR2A 3287/4885HTR6 2872/4885KDM4E 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.