SCHEMBL205646

SCHEMBL205646

NS(=O)(=O)Nc1ccccc1[N+](=O)[O-]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
TDP1 Q9NUW8 3/20 0.53
MAPK1 P28482 2/20 0.53
CASP7 P55210 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
CA1 P00915 3/20 0.50
KAT2B Q92831 2/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
CA2 P00918 2/20 0.49
KCNMA1 Q12791 1/20 0.47
MAPT P10636 3/20 0.47
PKM P14618 2/20 0.47
GAA P10253 1/20 0.47
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10586892 0.83 CRHBP (0.45) ALDH1A1TDP1MAPK1CASP7L3MBTL1
SCHEMBL29709934 0.81 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1CASP7L3MBTL1
SCHEMBL27182692 0.81 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1CASP7L3MBTL1
SCHEMBL27527027 0.81 MEN1 (0.54) ALDH1A1TDP1MAPK1CASP7L3MBTL1
SCHEMBL1039965 0.81 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1CASP7L3MBTL1
SCHEMBL11325141 0.79 CA2 (0.50) ALDH1A1TDP1MEN1KMT2ACA1
SCHEMBL30561863 0.79 ALDH1A1 (0.66) ALDH1A1TDP1MAPK1CASP7L3MBTL1
SCHEMBL2003165 0.79 ALDH1A1 (0.66) ALDH1A1TDP1MAPK1CASP7L3MBTL1
Sulfamide SCHEMBL28235502 0.78 KMT2A (0.61) ALDH1A1TDP1MEN1KMT2ACA1
SCHEMBL11166570 0.77 MAPT (0.50) ALDH1A1TDP1MAPK1CASP7L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2113 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524602-B2 Low molecular weight latex and toner compositions comprising the same XEROX CORPORATION (US) 2009-04-28 US claimed
US-7507517-B2 Toner processes XEROX CORPORATION (US) 2009-03-24 US claimed
US-7459258-B2 Toner processes XEROX CORPORATION (US) 2008-12-02 US claimed
US-20070082287-A1 Toner processes XEROX CORPORATION 2007-04-12 US claimed
US-20060286478-A1 Toner processes XEROX CORPORATION 2006-12-21 US claimed
US-20060286476-A1 manufactured under monomer-starved polymerization condition such as monomer feeding rate equal to or less than 0.516% per minute by weight of the monomer(s) to be fed; gloss, fusing performance, crease performance, stripping performance, document offset, vinyl offset, and parent charging etc. XEROX CORPORATION 2006-12-21 US claimed
EP-0458082-B1 Encapsulated toner compositions XEROX CORP (US) 1996-09-04 EP claimed
US-5204208-A Mixing at least two toners of different dyes or pigments XEROX CORPORATION (US) 1993-04-20 US claimed
US-5194356-A Toner compositions XEROX CORPORATION (US) 1993-03-16 US claimed
US-5164282-A Processes for the preparation of toners XEROX CORPORATION (US) 1992-11-17 US claimed
US-5104763-A ENCAPSULATED TONER COMPOSITIONS XEROX CORPORATION (US) 1992-04-14 US claimed
US-5082757-A Encapsulated toner compositions XEROX CORPORATION (US) 1992-01-21 US claimed
EP-0463412-A1 Magnetic colored encapsulated toner compositions XEROX CORPORATION (US) 1992-01-02 EP claimed
US-5077167-A Encapsulated toner compositions XEROX CORPORATION (US) 1991-12-31 US claimed
EP-0458082-A1 Encapsulated toner compositions XEROX CORPORATION (US) 1991-11-27 EP claimed
US-5045422-A Core-shell polymers, fluoropolymer core, pressure fixing, electrography XEROX CORPORATION (US) 1991-09-03 US claimed
US-5043240-A Encapsulated toner compositions XEROX CORPORATION (US) 1991-08-27 US claimed
US-5035970-A Encapsulated toner compositions and processes thereof XEROX CORPORATION (US) 1991-07-30 US claimed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed
US-5013630-A Encapsulated toner compositions XEROX CORPORATION (US) 1991-05-07 US claimed