Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1596479 | 0.93 | TSHR (0.46) | PKMCA12CA1CA2CA3 | |
| SCHEMBL14035533 | 0.89 | CA1 (0.42) | PKMCA12CA1CA2CA3 | |
| SCHEMBL31517020 | 0.88 | KDM4E (0.50) | PKMGAAMAPTKMT2ACYP1A2 | |
| SCHEMBL1596157 | 0.85 | PKM (0.50) | PKMCA12CA1CA2CA3 | |
| SCHEMBL10130846 | 0.83 | PDE4A (0.43) | PKMCA12CA1CA2CA3 | |
| SCHEMBL6243516 | 0.83 | PKM (0.48) | PKMCA12CA1CA2CA3 | |
| SCHEMBL21729392 | 0.83 | CA12 (0.48) | PKMCA12CA1CA2CA3 | |
| SCHEMBL16372693 | 0.83 | TUBB4A (0.55) | PKMCA12CA1CA2CA3 | |
| SCHEMBL1597087 | 0.82 | EGFR (0.41) | PKMGAAMAPTPTGS2ALOX5 | |
| SCHEMBL6717421 | 0.81 | PKM (0.47) | PKMCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008297-B2 | Bio-based, multi-aromatic compounds, and methods of making and using same | ROWAN UNIVERSITY (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200199087-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | ROWAN UNIVERSITY | 2020-06-25 | — | — | US | disclosed |
| EP-3625200-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | Rowan University (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018213236-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | ROWAN UNIVERSITY (US) | 2018-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008297-B2 | Bio-based, multi-aromatic compounds, and methods of making and using same | ALKBH3, ALKBH1, EWSR1 | PKM 348/4885CA12 3263/4885CA1 3552/4885 |
| US-20200199087-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | ALKBH3, ALKBH1, EWSR1 | PKM 348/4885CA12 3263/4885CA1 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.