⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654889 | 0.76 | FDPS (0.33) | — | |
| SCHEMBL246602 | 0.75 | LAP3 (0.37) | — | |
| SCHEMBL8170464 | 0.73 | TP53 (0.35) | — | |
| SCHEMBL11203187 | 0.73 | FOLH1 (0.35) | — | |
| SCHEMBL18486664 | 0.72 | FDPS (0.43) | — | |
| SCHEMBL2303259 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL2992910 | 0.68 | LAP3 (0.34) | — | |
| SCHEMBL1245730 | 0.67 | SLC7A5 (0.33) | — | |
| SCHEMBL2510899 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL3700078 | 0.66 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220095614-A1 | Antibiotic Compounds | THE GENERAL HOSPITAL CORPORATION | 2022-03-31 | — | — | US | disclosed |
| US-20200190009-A1 | Antibiotic Compounds | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-06-18 | — | — | US | disclosed |
| WO-2018213609-A1 | ANTIBIOTIC COMPOUNDS | AUSUBEL FREDERICK M (US) | 2018-11-22 | — | — | WO | disclosed |