SCHEMBL20565736

SCHEMBL20565736

N#Cc1cc(Sc2ccc(Cl)cc2)ccc1N

nearest known ligand 0.72

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.72
MAOB P27338 6/20 0.72
KDM4E B2RXH2 6/20 0.58
CYP1A2 P05177 5/20 0.58
CYP2C19 P33261 5/20 0.58
HPGD P15428 5/20 0.58
CYP3A4 P08684 4/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
MAPT P10636 3/20 0.58
CYP2D6 P10635 2/20 0.58
MCL1 Q07820 4/20 0.44
ALDH1A1 P00352 5/20 0.43
CYP2C9 P11712 4/20 0.43
GAA P10253 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8389901 0.85 MAOA (0.51) MAOAMAOBKDM4ECYP1A2CYP2C19
SCHEMBL12949048 0.84 MAOB (1.00) MAOAMAOBKDM4ECYP1A2CYP2C19
SCHEMBL8387387 0.83 MEN1 (0.55) MAOAMAOBKDM4ECYP1A2CYP2C19
SCHEMBL164458 0.79 TSHR (0.52) MAOAMAOBKDM4ECYP1A2CYP2C19
SCHEMBL29462390 0.79 TSHR (0.52) MAOAMAOBKDM4ECYP1A2CYP2C19
SCHEMBL7287393 0.79 MAOB (0.51) MAOAMAOBKDM4ECYP2C19HPGD
SCHEMBL8387640 0.78 MAOA (0.53) MAOAMAOBKDM4ECYP1A2CYP2C19
SCHEMBL20380325 0.78 MAOA (0.45) MAOAMAOBKDM4ECYP1A2CYP2C19
SCHEMBL3274518 0.77 MCL1 (0.51) MAOAMAOBKDM4ECYP1A2CYP2C19
SCHEMBL2657481 0.74 MAPT (0.56) MAOAMAOBKDM4ECYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405453-B1 A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2024-05-29 EP disclosed
CN-108884032-B Method for preparing poly (carbonate-etherimide) compounds PTT全球化学股份有限公司 2021-10-15 CN disclosed
US-10759904-B2 Method for preparing poly(carbonate-etherimide) compound PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2020-09-01 US disclosed
US-20190202980-A1 METHOD FOR PREPARING POLY(CARBONATE-ETHERIMIDE) COMPOUND PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2019-07-04 US disclosed
EP-3405453-A2 A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND PTT Global Chemical Public Company Limited (TH) 2018-11-28 EP disclosed