Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL626712 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HSD17B10BCAT2HNF4AMAPT | |
| Acetic Acid SCHEMBL28877658 | 0.92 | ALDH1A1 (0.54) | ALDH1A1HSD17B10BCAT2HNF4AMAPT | |
| SCHEMBL29564016 | 0.91 | ALDH1A1 (0.68) | ALDH1A1HSD17B10BCAT2MAPTL3MBTL1 | |
| SCHEMBL169282 | 0.91 | ALDH1A1 (0.68) | ALDH1A1HSD17B10BCAT2MAPTL3MBTL1 | |
| Biphenyl SCHEMBL29177662 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10MAPTL3MBTL1HPGD | |
| Fluoride SCHEMBL29111498 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10BCAT2MAPTL3MBTL1 | |
| Water SCHEMBL6830763 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10BCAT2MAPTL3MBTL1 | |
| SCHEMBL27599082 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10BCAT2MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9614559 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10BCAT2MAPTL3MBTL1 | |
| SCHEMBL10909218 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10BCAT2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405453-B1 | A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND | PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) | 2024-05-29 | — | — | EP | disclosed |
| CN-108884032-B | Method for preparing poly (carbonate-etherimide) compounds | PTT全球化学股份有限公司 | 2021-10-15 | — | — | CN | disclosed |
| US-10759904-B2 | Method for preparing poly(carbonate-etherimide) compound | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2020-09-01 | — | — | US | disclosed |
| US-20190202980-A1 | METHOD FOR PREPARING POLY(CARBONATE-ETHERIMIDE) COMPOUND | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2019-07-04 | — | — | US | disclosed |
| EP-3405453-A2 | A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND | PTT Global Chemical Public Company Limited (TH) | 2018-11-28 | — | — | EP | disclosed |