Acetic Acid

Acetic Acid

SCHEMBL28877658

CC(=O)O.CC(=O)O.CC(=O)O.CC(=O)O.Nc1cccc(-c2ccccc2)c1N

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
HSD17B10 Q99714 2/20 0.54
BCAT2 O15382 1/20 0.46
MAPT P10636 3/20 0.45
KDM4E B2RXH2 2/20 0.45
LMNA P02545 1/20 0.45
PKM P14618 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
HNF4A P41235 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
MAPK13 O15264 1/20 0.40
MAPK12 P53778 1/20 0.40
MAPK11 Q15759 1/20 0.40
MAPK14 Q16539 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HSP90AA1 P07900 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL20565740 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10BCAT2MAPTKDM4E
Bicarbonate SCHEMBL626712 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10BCAT2MAPTKDM4E
Ethane SCHEMBL28765226 0.88 ALDH1A1 (0.62) ALDH1A1HSD17B10BCAT2MAPTKDM4E
SCHEMBL29564016 0.88 ALDH1A1 (0.68) ALDH1A1HSD17B10BCAT2MAPTKDM4E
SCHEMBL169282 0.88 ALDH1A1 (0.68) ALDH1A1HSD17B10BCAT2MAPTKDM4E
Acetic Acid SCHEMBL5748782 0.86 ALDH1A1 (0.74) ALDH1A1HSD17B10BCAT2MAPTKDM4E
Biphenyl SCHEMBL29177662 0.86 ALDH1A1 (0.65) ALDH1A1HSD17B10MAPTKDM4ELMNA
SCHEMBL10909218 0.86 ALDH1A1 (0.65) ALDH1A1HSD17B10BCAT2MAPTKDM4E
Fluoride SCHEMBL29111498 0.86 ALDH1A1 (0.65) ALDH1A1HSD17B10BCAT2MAPTKDM4E
Water SCHEMBL6830763 0.86 ALDH1A1 (0.65) ALDH1A1HSD17B10BCAT2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-218261085-U Special-shaped copper strip cleaning line 金昌镍都矿山实业有限公司 2023-01-10 CN disclosed
CN-115258771-A Special-shaped copper strip cleaning line and cleaning method 金昌镍都矿山实业有限公司 2022-11-01 CN disclosed