Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29739710 | 0.90 | KMT2A (0.53) | KMT2ADHODHALDH1A1GAAKDM4E | |
| SCHEMBL29739233 | 0.85 | RAB9A (0.56) | KMT2ADHODHALDH1A1GAAKDM4E | |
| SCHEMBL20565563 | 0.85 | ALDH1A1 (0.52) | KMT2AALDH1A1GAAKDM4EHPGD | |
| SCHEMBL7383350 | 0.84 | DHODH (0.51) | KMT2ADHODHALDH1A1GAAKDM4E | |
| SCHEMBL17372913 | 0.84 | MEN1 (0.56) | KMT2ADHODHALDH1A1GAAKDM4E | |
| SCHEMBL17372922 | 0.84 | HTT (0.56) | KMT2AALDH1A1GAAATMRAB9A | |
| SCHEMBL21305450 | 0.83 | KMT2A (0.54) | KMT2ADHODHALDH1A1GAAKDM4E | |
| SCHEMBL15821915 | 0.83 | RAB9A (0.59) | KMT2AALDH1A1GAAKDM4EHPGD | |
| SCHEMBL6676510 | 0.83 | IGF2BP2 (0.62) | DHODHGAAHPGDIGF2BP2CYP1A2 | |
| SCHEMBL16907381 | 0.83 | RAB9A (0.56) | KMT2ADHODHALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157922-B1 | PYRAZOLO-PYRIDINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2018-11-28 | — | — | EP | disclosed |