Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.54 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383350 | 0.86 | DHODH (0.51) | IGF2BP2MAPTPOLBKCNK2KCNK10 | |
| SCHEMBL28758859 | 0.83 | MAPT (0.57) | MAPTCYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL30739593 | 0.83 | CTNNB1 (0.55) | IGF2BP2MAPTPOLBTP53TRPV1 | |
| SCHEMBL11826733 | 0.83 | RAB9A (0.65) | MAPTCYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL2913292 | 0.83 | SMN1; SMN2 (0.51) | IGF2BP2MAPTCYP1A2CYP2C19POLB | |
| SCHEMBL20565746 | 0.83 | KMT2A (0.53) | IGF2BP2MAPTCYP1A2POLBHPGD | |
| SCHEMBL28139470 | 0.81 | DYRK1A (0.51) | IGF2BP2POLBHPGDDHODHGAA | |
| SCHEMBL19411046 | 0.80 | DHODH (0.46) | IGF2BP2CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL29522124 | 0.80 | DHODH (0.46) | IGF2BP2CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL29049895 | 0.80 | MAPT (0.57) | MAPTCYP1A2CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427705-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003026415-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |