SCHEMBL2056624

SCHEMBL2056624

NOC[C@@H]1O[C@H](n2ccc(=O)[nH]c2=O)CC1O

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.64
P2RY2 P41231 3/20 0.51
P2RY4 P51582 3/20 0.51
P2RY6 Q15077 2/20 0.51
TYMS P04818 5/20 0.48
SLC28A1 O00337 1/20 0.46
SLC28A2 O43868 1/20 0.46
SLC29A1 Q99808 1/20 0.46
SLC28A3 Q9HAS3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2009956 1.00 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL140597 0.89 DUT (0.66) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL6034461 0.89 DUT (0.66) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL13153886 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL438240 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL3716323 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL4298071 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL15798318 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL1255927 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL26757491 0.88 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110104754-A1 CELL CULTURE MEDIUM GENETIX LIMITED 2011-05-05 US disclosed
EP-1818392-B1 Cell culture medium GENETIX LTD (GB) 2010-08-25 EP disclosed
US-20070212778-A1 Cell culture medium GENETIX LIMITED 2007-09-13 US disclosed
EP-1818392-A1 Cell culture medium Genetix Limited (GB) 2007-08-15 EP disclosed
US-6277576-B1 MODIFICATION OF NUCLEIC ACIDS (CONTAINING ELECTRON DONOR/ ACCEPTOR MOIETY ATTACHED) AT SPECIFIC SITES WITH REDOX ACTIVE MOIETIES, TRANSITION METAL COMPLEXES, WHICH ARE TEMPLATES CAPABLE OF TRANSFERRING ELECTRONS OVER LARGE DISTANCES CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-08-21 US disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed