Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.64 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.49 |
| ▸ | TYMS | P04818 | 5/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034461 | 0.89 | DUT (0.66) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL140597 | 0.89 | DUT (0.66) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL15798318 | 0.88 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL1255927 | 0.88 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL2056624 | 0.88 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL13153886 | 0.88 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL3716323 | 0.88 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL2009956 | 0.88 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL438240 | 0.88 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL26923594 | 0.88 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221468-A1 | Autonomously Replicating KSHV CIS-Acting Elements | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2009-09-03 | — | — | US | disclosed |
| US-20080161260-A1 | Contacting the genomic DNA with monoclonal anti-HdU antibodies; contacting the anti-HdU antibodies bound to the HdU-containing DNA with a compound that is converted to a light-emitting product; determining the intensity of the chemiluminescent signal | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
| WO-2008024995-A2 | METHOD FOR DETECTING AND QUANTIFYING CELL PROLIFERATION IN VIVO | WYETH (US) | 2008-02-28 | — | — | WO | disclosed |
| WO-2007047759-A1 | AUTONOMOUSLY REPLICATING KSHV CIS-ACTING ELEMENTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-04-26 | — | — | WO | disclosed |