Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.42 |
| ▸ | PTGFR | P43088 | 3/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729446 | 0.82 | CA1 (0.53) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL9386169 | 0.76 | KMT2A (0.44) | NFKB1MAPTHTTPTPN1LMNA | |
| SCHEMBL6561859 | 0.75 | CA1 (0.56) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL7455794 | 0.75 | CA1 (0.56) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL5712170 | 0.73 | CA1 (0.55) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL459291 | 0.73 | NFKB1 (0.75) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL31197561 | 0.73 | NFKB1 (0.75) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL69543 | 0.73 | NFKB1 (0.75) | CA1CA2NFKB1CA4PTGER3 | |
| SCHEMBL7476350 | 0.73 | ALDH1A1 (0.48) | CA1CA2NFKB1CA4MAPT | |
| SCHEMBL10351248 | 0.72 | PTGER3 (0.58) | CA1CA2NFKB1CA4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186268-B1 | ESTERS OF STEROIDAL LACTAM AND BIS(2-CHLOROETHYL) AMINOPHENOXY PROPANOIC ACID DERIVATIVES | GALENICA S A (GR) | 2018-11-28 | — | — | EP | disclosed |