SCHEMBL20566877

SCHEMBL20566877

CC1CN(Cc2cccc(Oc3ccc(F)cc3)c2)CCN1C(=O)n1ccc(C(=O)O)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 1.00
FAAH O00519 8/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20566876 1.00 MGLL (1.00) MGLLFAAH
SCHEMBL20567075 1.00 MGLL (1.00) MGLLFAAH
SCHEMBL30420434 1.00 MGLL (1.00) MGLLFAAH
SCHEMBL30419885 1.00 MGLL (1.00) MGLLFAAH
SCHEMBL25830323 0.93 MGLL (0.88) MGLLFAAH
SCHEMBL25830322 0.93 MGLL (0.88) MGLLFAAH
SCHEMBL24235966 0.92 MGLL (0.86) MGLLFAAH
SCHEMBL20567668 0.92 MGLL (0.85) MGLLFAAH
SCHEMBL20567669 0.92 MGLL (0.85) MGLLFAAH
SCHEMBL30420719 0.92 MGLL (0.85) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219897-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2023-07-13 US disclosed
US-11655217-B2 Pyrazole MAGL inhibitors H. LUNDBECK A/S (DK) 2023-05-23 US disclosed
US-20210053960-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2021-02-25 US disclosed
US-10927105-B1 Pyrazole MAGL inhibitors LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) 2021-02-23 US disclosed
US-10266497-B2 Pyrazole MAGL inhibitors ABIDE THERAPEUTICS, INC. (US) 2019-04-23 US disclosed
US-20180339970-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2018-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180339970-A1 PYRAZOLE MAGL INHIBITORS MGLL, PNLIP, LPL MGLL 1/4885FAAH 33/4885
US-20230219897-A1 PYRAZOLE MAGL INHIBITORS MGLL, PNLIP, LPL MGLL 1/4885FAAH 33/4885
US-10266497-B2 Pyrazole MAGL inhibitors MGLL, PNLIP, LPL MGLL 1/4885FAAH 33/4885
US-20210053960-A1 PYRAZOLE MAGL INHIBITORS MGLL, PNLIP, LPL MGLL 1/4885FAAH 33/4885
US-11655217-B2 Pyrazole MAGL inhibitors MGLL, PNLIP, LPL MGLL 1/4885FAAH 32/4885
US-10927105-B1 Pyrazole MAGL inhibitors MGLL, PNLIP, LPL MGLL 1/4885FAAH 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.