Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20567443 | 0.88 | MAPT (0.68) | PPARGCYP3A4KDM4EALDH1A1HPGD | |
| SCHEMBL20567284 | 0.85 | L3MBTL1 (0.58) | L3MBTL1PPARGCYP3A4KDM4EALDH1A1 | |
| SCHEMBL20568031 | 0.81 | PTGS1 (0.42) | L3MBTL1PPARGCYP3A4KDM4EALDH1A1 | |
| SCHEMBL11029670 | 0.78 | MAOA (0.54) | POLBNPC1RAB9A | |
| SCHEMBL11030634 | 0.76 | MAOA (0.41) | L3MBTL1POLB | |
| Flavodic Acid SCHEMBL867342 | 0.76 | KDM4E (0.76) | L3MBTL1PPARGCYP3A4KDM4EALDH1A1 | |
| SCHEMBL4225411 | 0.75 | PPARG (0.73) | L3MBTL1PPARGCYP3A4KDM4EALDH1A1 | |
| SCHEMBL11029063 | 0.75 | MAOA (0.40) | CYP1A2NPC1ABCG2RAB9ACYP1A1 | |
| Flavodic Acid SCHEMBL29357623 | 0.74 | KDM4E (0.71) | L3MBTL1PPARGCYP3A4KDM4EALDH1A1 | |
| SCHEMBL11029434 | 0.73 | MAOA (0.42) | CYP3A4KDM4EALDH1A1HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10383844-B2 | Methods for treating pulmonary fibrosis using chromenone derivatives | College of Medicine Pochon Cha University Industry—Academic Cooperation (KR) | 2019-08-20 | — | — | US | disclosed |
| US-10383844-B2 | Methods for treating pulmonary fibrosis using chromenone derivatives | College of Medicine Pochon Cha University Industry—Academic Cooperation (KR) | 2019-08-20 | — | — | US | disclosed |
| US-20180338948-A1 | METHODS FOR TREATING PULMONARY FIBROSIS USING CHROMENONE DERIVATIVES | COLL, MEDICINE POCHON CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2018-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10383844-B2 | Methods for treating pulmonary fibrosis using chromenone derivatives | HSPB1, HSF1, HSP90AB1 | L3MBTL1 4105/4885PPARG 247/4885CYP3A4 3931/4885 |
| US-20180338948-A1 | METHODS FOR TREATING PULMONARY FIBROSIS USING CHROMENONE DERIVATIVES | HSPB1, HSF1, HSP90AB1 | L3MBTL1 4105/4885PPARG 247/4885CYP3A4 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.