SCHEMBL20567484

SCHEMBL20567484

CCCC1=NS(=O)(=O)c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.54
KCNA3 P22001 3/20 0.51
ALDH1A1 P00352 6/20 0.50
HSD17B10 Q99714 4/20 0.50
NPC1 O15118 2/20 0.50
TP53 P04637 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HPGD P15428 2/20 0.50
GAA P10253 3/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
POLB P06746 1/20 0.41
KDM4E B2RXH2 2/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956475 0.90 PKM (0.51) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL7693631 0.88 PKM (0.50) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL14374689 0.85 PKM (0.57) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL27273890 0.79 PKM (0.48) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL9786855 0.78 PKM (0.49) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL28297387 0.77 PKM (0.49) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL13240433 0.77 PKM (0.49) PKMKCNA3ALDH1A1HSD17B10NPC1
Hydrochloric Acid SCHEMBL7773232 0.76 PKM (0.47) PKMKCNA3ALDH1A1HSD17B10SMN1; SMN2
Hydrochloric Acid SCHEMBL8956567 0.75 PKM (0.46) PKMKCNA3ALDH1A1HSD17B10HPGD
SCHEMBL10572695 0.74 PKM (0.45) PKMKCNA3ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180340138-A1 ENZYME STABILIZERS HENKEL AG & CO. KGAA (DE) 2018-11-29 US claimed
CN-1017584-B Plant protection agents for fungi and bacteria containing benzoisothiazoloxime derivatives AGRO KANESHO CO LTD (JP) 1992-07-29 CN claimed
CN-1030413-A Plant protection agents for controlling fungi and bacteria AGRO KANESHO CO LTD (JP) 1989-01-18 CN claimed
CN-1020725-C PROCESS FOR PREPARING BENZOISOTHIAZOLE OXIMES DERIVATIVES ARO KANESHO CO LTD (JP) 1993-05-19 CN disclosed
CN-1019941-C Method for biologically preventing and treating rice blast by benzisothiazole AGRO KANESHO CO LTD (JP) 1993-03-03 CN disclosed
CN-1017584-B Plant protection agents for fungi and bacteria containing benzoisothiazoloxime derivatives AGRO KANESHO CO LTD (JP) 1992-07-29 CN disclosed
CN-1057943-A The method of control rice blast AGRO KANESHO CO LTD (JP) 1992-01-22 CN disclosed
CN-1056694-A The preparation method of benzoisothiazole oximes derivatives ARO KANESHO CO LTD (JP) 1991-12-04 CN disclosed
CN-1030413-A Plant protection agents for controlling fungi and bacteria AGRO KANESHO CO LTD (JP) 1989-01-18 CN disclosed