SCHEMBL7693631

SCHEMBL7693631

CCCCCC1=NS(=O)(=O)c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.50
KCNA3 P22001 3/20 0.47
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 3/20 0.44
NPC1 O15118 2/20 0.44
TP53 P04637 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 2/20 0.44
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
MAPT P10636 2/20 0.43
LMNA P02545 2/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956475 0.95 PKM (0.51) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL20567484 0.88 PKM (0.54) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL14374689 0.81 PKM (0.57) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL6243131 0.75 PKM (0.72) PKMKCNA3ALDH1A1HSD17B10RAB9A
SCHEMBL9786855 0.74 PKM (0.49) PKMKCNA3ALDH1A1HSD17B10NPC1
SCHEMBL3853432 0.74 KCNA3 (0.55) PKMKCNA3ALDH1A1NPC1SMN1; SMN2
SCHEMBL3853334 0.74 MAPT (0.51) PKMALDH1A1HSD17B10NPC1TP53
SCHEMBL13240433 0.73 PKM (0.49) PKMKCNA3ALDH1A1HSD17B10NPC1
Hydrochloric Acid SCHEMBL7773232 0.72 PKM (0.47) PKMKCNA3ALDH1A1HSD17B10SMN1; SMN2
Hydrochloric Acid SCHEMBL8956567 0.71 PKM (0.46) PKMKCNA3ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1017584-B Plant protection agents for fungi and bacteria containing benzoisothiazoloxime derivatives AGRO KANESHO CO LTD (JP) 1992-07-29 CN claimed
CN-1030413-A Plant protection agents for controlling fungi and bacteria AGRO KANESHO CO LTD (JP) 1989-01-18 CN claimed
US-6458962-B1 VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION 2002-10-01 US disclosed
CN-1020725-C PROCESS FOR PREPARING BENZOISOTHIAZOLE OXIMES DERIVATIVES ARO KANESHO CO LTD (JP) 1993-05-19 CN disclosed
CN-1019941-C Method for biologically preventing and treating rice blast by benzisothiazole AGRO KANESHO CO LTD (JP) 1993-03-03 CN disclosed
CN-1017584-B Plant protection agents for fungi and bacteria containing benzoisothiazoloxime derivatives AGRO KANESHO CO LTD (JP) 1992-07-29 CN disclosed
CN-1057943-A The method of control rice blast AGRO KANESHO CO LTD (JP) 1992-01-22 CN disclosed
CN-1056694-A The preparation method of benzoisothiazole oximes derivatives ARO KANESHO CO LTD (JP) 1991-12-04 CN disclosed
CN-1030413-A Plant protection agents for controlling fungi and bacteria AGRO KANESHO CO LTD (JP) 1989-01-18 CN disclosed