Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358251 | 0.83 | TDP1 (0.68) | LMNATDP1SMN1; SMN2GAACA1 | |
| SCHEMBL9131405 | 0.82 | POLB (0.79) | LMNATDP1SMN1; SMN2GAACA1 | |
| SCHEMBL2697108 | 0.80 | TSHR (0.69) | LMNATDP1SMN1; SMN2GAACA1 | |
| SCHEMBL31424039 | 0.79 | CA1 (0.55) | LMNATDP1SMN1; SMN2GAACA1 | |
| SCHEMBL25870930 | 0.79 | CA12 (0.72) | LMNATDP1SMN1; SMN2GAACA1 | |
| SCHEMBL25241197 | 0.78 | KMT2A (0.71) | LMNATDP1SMN1; SMN2GAAPOLB | |
| SCHEMBL6396355 | 0.78 | KAT6A (0.78) | LMNATDP1SMN1; SMN2GAAKMT2A | |
| SCHEMBL25248605 | 0.77 | ALDH1A1 (0.74) | LMNATDP1SMN1; SMN2GAACA1 | |
| SCHEMBL26104435 | 0.77 | GAA (0.65) | LMNASMN1; SMN2GAACA1CA2 | |
| SCHEMBL25872128 | 0.76 | KAT6A (0.60) | LMNATDP1SMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180339963-A1 | ANTICONVULSANT CARBAMATE DERIVATIVES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2018-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180339963-A1 | ANTICONVULSANT CARBAMATE DERIVATIVES | CNR2, GRIK5, GRIK4 | LMNA 4351/4885TDP1 3049/4885SMN1; SMN2 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.