Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17688763 | 0.88 | PTGS2 (0.32) | POLBLRRK2USP1KCNH2 | |
| SCHEMBL21761790 | 0.87 | RORC (0.31) | POLBLRRK2RORC | |
| SCHEMBL21750096 | 0.87 | EGLN1 (0.37) | POLBLRRK2USP1RORC | |
| SCHEMBL21750111 | 0.86 | USP1 (0.33) | POLBLRRK2USP1RORC | |
| SCHEMBL22912032 | 0.86 | LRRK2 (0.36) | LRRK2USP1 | |
| SCHEMBL21761767 | 0.85 | RORC (0.32) | USP1RORC | |
| SCHEMBL20553672 | 0.85 | ELANE (0.34) | LRRK2RORC | |
| SCHEMBL22912035 | 0.85 | RORC (0.33) | POLBRORC | |
| SCHEMBL20547490 | 0.84 | CNR2 (0.33) | LRRK2RORCKCNH2 | |
| SCHEMBL30958294 | 0.84 | CNR2 (0.33) | LRRK2RORCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018215304-A1 | TETRACYCLIC PYRIDAZINE SULPHUR CONTAINING COMPOUNDS AND THEIR USE AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-29 | — | — | WO | disclosed |