SCHEMBL20568397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20569633	0.83	LMNA (0.44)	MAPK14
	SCHEMBL20568333	0.81	GPR35 (0.43)	CA12ALPLRXRAHCAR2FABP4
	SCHEMBL20568514	0.77	PRKAA2 (0.37)	PRKAA2RPA1RXRAPTGS1PTGS2
	SCHEMBL29568998	0.73	MCL1 (0.50)	PRKAA2RPA1RXRAMCL1
	SCHEMBL18919773	0.73	MCL1 (0.50)	PRKAA2RPA1RXRAMCL1
	SCHEMBL20568313	0.72	GPR35 (0.60)	PRKAA2RPA1PTGS1PTGS2MAPK11
	SCHEMBL20568815	0.72	CSNK1E (0.36)	RPA1PTGS1PTGS2MAPK11MAPK14
	SCHEMBL3946719	0.68	HCAR2 (0.50)	HCAR2
	SCHEMBL23327695	0.67	GPR35 (0.52)	MAPK11MAPK14MKNK1MKNK2
	SCHEMBL1744135	0.67	PRKAA2 (0.67)	PRKAA2RXRANR1I2NR4A2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.