Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 15/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488039 | 0.78 | DAO (1.00) | DAO | |
| SCHEMBL20569899 | 0.76 | DAO (0.75) | DAO | |
| SCHEMBL20569629 | 0.74 | DAO (0.71) | DAO | |
| SCHEMBL10939300 | 0.73 | NOTUM (0.58) | DAOMAOAMAOB | |
| SCHEMBL20569533 | 0.73 | DAO (0.63) | DAOERCC1ERCC4MCL1 | |
| SCHEMBL7256428 | 0.72 | — | — | |
| SCHEMBL20570319 | 0.70 | DAO (0.44) | DAOMCL1 | |
| SCHEMBL14485851 | 0.70 | DAO (1.00) | DAO | |
| SCHEMBL14488165 | 0.69 | DAO (1.00) | DAO | |
| SCHEMBL481976 | 0.68 | MAOA (0.64) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |