SCHEMBL481976

SCHEMBL481976

Clc1ccc(Sc2ccc(Cl)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.64
MAOB P27338 3/20 0.64
LMNA P02545 1/20 0.57
CYP2A6 P11509 1/20 0.57
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPT P10636 2/20 0.50
HAO1 Q9UJM8 1/20 0.50
NPC1 O15118 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CHRNA7 P36544 1/20 0.50
CYP3A4 P08684 2/20 0.47
NR1H2 P55055 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
RHEB Q15382 1/20 0.47
CYP2C9 P11712 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9476350 1.00 MAOA (0.64) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL9475224 1.00 MAOA (0.64) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL6546576 0.97 MAOA (0.61) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL6546581 0.97 MAOA (0.61) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL3282907 0.91 MAOA (0.56) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL9474836 0.91 MAOA (0.56) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL18561707 0.88 CHRNA7 (0.64) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL1931122 0.88 CHRNA7 (0.64) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL5889412 0.86 IDO1 (0.68) MAOAMAOBLMNACYP2A6MEN1
SCHEMBL9418094 0.86 CYP3A4 (0.74) MAOAMAOBLMNACYP2A6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118390125-B Copper electroplating additive suitable for IC carrier plate and preparation method and application thereof 深圳市板明科技股份有限公司 2024-08-16 CN claimed
CN-118459946-A High-light-shielding antioxidant PET black master batch and preparation method thereof 浙江莲胜新材料科技有限公司 2024-08-09 CN claimed
CN-115745856-B Cyclohexyl-containing phthalonitrile monomer and preparation method and application thereof 万华化学集团股份有限公司 2024-05-03 CN claimed
CN-117384132-A Azaaromatic ring pyridine salt and application thereof in olefin functionalization reaction 国科大杭州高等研究院 2024-01-12 CN claimed
EP-3774727-B1 CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFOXIDE CRYSTALS (C) BASF SE (DE) 2023-09-13 EP claimed
CN-115745856-A Cyclohexyl phthalonitrile-containing monomer and preparation method and application thereof 万华化学集团股份有限公司 2023-03-07 CN claimed
US-20220127221-A1 CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFOXIDE CRYSTALS (C) BASF SE (DE) 2022-04-28 US claimed
US-10975024-B2 Crystal composition (CC) comprising 4,4#-dichlorodiphenylsulfoxide crystals (C) BASF SE (DE) 2021-04-13 US claimed
EP-3774727-A1 CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFOXIDE CRYSTALS (C) BASF SE (DE) 2021-02-17 EP claimed
WO-2020161100-A1 CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFOXIDE CRYSTALS (C) BASF SE (DE) 2020-08-13 WO claimed
US-20060084785-A1 Polyarylene sulfide and process for producing the same KUREHA CORPORATION (JP) 2006-04-20 US claimed
EP-1577336-A1 POLYARYLENE SULFIDE AND PROCESS FOR PRODUCING THE SAME Kureha Chemical Industry Co., Ltd. (JP) 2005-09-21 EP claimed
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP claimed
EP-0262061-B1 PROCESS FOR STABILIZING CHLORINATION MIXTURES OF PHENOL AND/OR CHLOROPHENOLS RHONE-POULENC CHIMIE (FR) 1993-02-24 EP claimed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US claimed
US-4853153-A USING REDUCING AGENT AND CHLORINATED CYCLIC KETONE RHONE-POULENC CHIMIE (FR) 1989-08-01 US claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
US-4092369-A CHLORINATION OF CHLOROAROMATIC COMPOUND, ORGANIC SULFIDE CATALYST HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-05-30 US claimed
US-4010214-A FROM P-XYLENE AND CHLORINE, IRON HALIDE ANDOR ANTIMONY HALIDE AND ORGANIC SULFUR COMPOUND CATALYST HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-03-01 US claimed
US-3944664-A B-EXOTOXIN OR SALTS AND 1,1-BIS(P-CHLOROPHENYL)ETHANOL, BIS(P-CHLOROPHENYL) SULFIDE OR BIS(P-CHLOROPHENOXY)METHANE SANDOZ, INC. (US) 1976-03-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10975024-B2 Crystal composition (CC) comprising 4,4#-dichlorodiphenylsulfoxide crystals (C) CCR4, SCO2, CYCS MAOA 4611/4885MAOB 4358/4885LMNA 4265/4885
US-20220127221-A1 CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFOXIDE CRYSTALS (C) CCR4, SCO2, CYCS MAOA 4535/4885MAOB 4256/4885LMNA 4269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.