Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | CD74 | P04233 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570142 | 0.87 | HTT (0.52) | IDO1YTHDC1TDP1KMT2ACYP1A2 | |
| SCHEMBL20569345 | 0.84 | BRD4 (0.44) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20570136 | 0.79 | TSHR (0.53) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| Iodide SCHEMBL29037976 | 0.76 | TDP1 (0.61) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL696380 | 0.74 | OPRD1 (0.52) | IDO1OPRD1LOXL2YTHDC1CYP4F2 | |
| SCHEMBL7830882 | 0.73 | LOXL2 (0.62) | IDO1LOXL2CYP4F2CYP4A11ABHD6 | |
| SCHEMBL696367 | 0.73 | OPRD1 (0.51) | IDO1OPRD1LOXL2YTHDC1KMT2A | |
| SCHEMBL14987126 | 0.73 | HTT (0.71) | IDO1LOXL2CYP4F2CYP4A11ABHD6 | |
| SCHEMBL20570065 | 0.73 | CYP1A2 (0.48) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL697926 | 0.73 | RAB9A (0.48) | OPRD1YTHDC1TDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |