⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633078 | 0.92 | GBA1 (0.32) | — | |
| SCHEMBL786721 | 0.86 | FAAH (0.34) | — | |
| SCHEMBL2922550 | 0.86 | FAAH (0.34) | — | |
| SCHEMBL787106 | 0.86 | FAAH (0.34) | — | |
| SCHEMBL4282749 | 0.84 | GBA1 (0.43) | — | |
| SCHEMBL369965 | 0.84 | GBA1 (0.43) | — | |
| SCHEMBL5303207 | 0.84 | GBA1 (0.43) | — | |
| SCHEMBL7355166 | 0.77 | SMN1; SMN2 (0.32) | — | |
| Water SCHEMBL28388741 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL28513909 | 0.75 | GBA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424965-B1 | CROSSLINK AGENTS AND ITS USE | BAUSCH & LOMB (US) | 2020-05-13 | — | — | EP | disclosed |
| EP-3424965-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | Bausch & Lomb Incorporated (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-2167555-B1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | BAUSCH & LOMB (US) | 2018-10-10 | — | — | EP | disclosed |
| US-8252850-B2 | Crosslink agents | BAUSCH & LOMB INCORPORATED (US) | 2012-08-28 | — | — | US | disclosed |
| US-20110105779-A1 | CROSSLINK AGENTS | ORAPHARMA, INC. | 2011-05-05 | — | — | US | disclosed |
| US-7901073-B2 | Silicone hydrogel with composite hydrophilic and silicone polymers prepared with selective crosslink agents | BAUSCH & LOMB INCORPORATED (US) | 2011-03-08 | — | — | US | disclosed |
| EP-2167555-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | Bausch & Lomb Incorporated (US) | 2010-03-31 | — | — | EP | disclosed |
| US-20090018233-A1 | Crosslink Agents and Dual Radical Cure Polymer | SOLTA MEDICAL, INC. | 2009-01-15 | — | — | US | disclosed |
| WO-2009009527-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | BAUSCH & LOMB INCORPORATED (US) | 2009-01-15 | — | — | WO | disclosed |