SCHEMBL633078

SCHEMBL633078

C=CC1CCN(CCCCCCN2CCC(C=C)C2=O)C1=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.32
PIK3CD O00329 1/20 0.30
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL786721 0.93 FAAH (0.34) KMT2A
SCHEMBL2922550 0.93 FAAH (0.34) KMT2A
SCHEMBL787106 0.93 FAAH (0.34) KMT2A
SCHEMBL4282749 0.92 GBA1 (0.43) GBA1
SCHEMBL2056924 0.92
SCHEMBL369965 0.92 GBA1 (0.43) GBA1
SCHEMBL5303207 0.92 GBA1 (0.43) GBA1
SCHEMBL7355166 0.84 SMN1; SMN2 (0.32) MEN1KMT2A
Water SCHEMBL28388741 0.82 ALDH1A1 (0.33) MEN1KMT2A
SCHEMBL28513909 0.81 GBA1 (0.40) GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017827-A1 Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them IVOCLAR VIVADENT AG (LI) 2025-01-16 US claimed
EP-4488243-A1 ACID-STABLE GLASS FILLERS AND SELF-ADHESIVE DENTAL COMPOSITE CEMENTS CONTAINING SAME HAVING GOOD TRANSPARENCY Ivoclar Vivadent AG (LI) 2025-01-08 EP claimed
US-20240158614-A1 STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY IVOCLAR VIVADENT AG (LI) 2024-05-16 US claimed
EP-4356893-A1 STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY Ivoclar Vivadent AG (LI) 2024-04-24 EP claimed
EP-4205723-A1 HIGH TRANSPARENCY, SULPHATE-CONTAINING OR PHOSPHATE-CONTAINING DENTAL SELF-ADHERING COMPOSITE Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
EP-4205724-A1 SELF-ADHESIVE DENTAL COMPOSITE CEMENTS WITH GOOD TRANSPARENCY BASED ON ACID-TREATED FILLERS Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
EP-4205722-A1 SELF-ADHESIVE DENTAL COMPOSITE WITH GOOD TRANSPARENCY Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
CN-116350518-A Self-adhesive dental composite cement with good transparency 义获嘉伟瓦登特公司 2023-06-30 CN claimed
CN-116350519-A Sulfate-or phosphate-containing self-adhesive dental composite cements with good transparency 义获嘉伟瓦登特公司 2023-06-30 CN claimed
US-20230201083-A1 SELF-ADHESIVE DENTAL COMPOSITE CEMENT WITH GOOD TRANSPARENCY BASED ON ACID-TREATED FILLERS IVOCLAR VIVADENT AG (LI) 2023-06-29 US claimed
US-20070027229-A1 Photopolymerizable dental materials with bisacylphosphine oxides as initiators IVOCLAR VIVADENT AG (LI) 2007-02-01 US claimed
EP-1413569-B1 Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials IVOCLAR VIVADENT AG (LI) 2006-12-13 EP claimed
US-20060178469-A1 Polymerizable cyclopropyl acrylates IVOCLAR VIVADENT AG 2006-08-10 US claimed
EP-1674066-A1 Self-etching dental materials based on (meth)acrylamidophosphates Ivoclar Vivadent AG (LI) 2006-06-28 EP claimed
EP-1374829-B1 Dental material on the basis of acryloester phosphonic acid IVOCLAR VIVADENT AG (LI) 2005-11-02 EP claimed
US-6900251-B2 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2005-05-31 US claimed
EP-1413569-A1 Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials Ivoclar Vivadent AG (LI) 2004-04-28 EP claimed
US-20040077882-A1 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials IVOCLAR VIVADENT AG (LI) 2004-04-22 US claimed
US-20040077754-A1 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2004-04-22 US claimed
EP-1374829-A1 Dental material on the basis of acryloester phosphonic acid Ivoclar Vivadent AG (LI) 2004-01-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077882-A1 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials SCO2, CBR1, CORO1C GBA1 788/4885PIK3CD 3573/4885MEN1 3520/4885
US-20040077754-A1 Dental materials based on acrylic-ester phosphonic acids PHOSPHO1, RER1, PTGER1 GBA1 1641/4885PIK3CD 130/4885MEN1 1850/4885
US-20230201083-A1 SELF-ADHESIVE DENTAL COMPOSITE CEMENT WITH GOOD TRANSPARENCY BASED ON ACID-TREATED FILLERS CDH1, VCL, RARA GBA1 1398/4885PIK3CD 3180/4885MEN1 1601/4885
US-20060178469-A1 Polymerizable cyclopropyl acrylates CBR3, CBR1, ACAD9 GBA1 532/4885PIK3CD 4078/4885MEN1 3205/4885
US-20250017827-A1 Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them HAO2, HAO1, CDH1 GBA1 1957/4885PIK3CD 3571/4885MEN1 2245/4885
US-20070027229-A1 Photopolymerizable dental materials with bisacylphosphine oxides as initiators PRXL2A, PGM2, PAM GBA1 516/4885PIK3CD 2173/4885MEN1 4547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.