Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.57 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.55 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20568991 | 0.87 | HDAC3 (0.52) | — | |
| SCHEMBL20570273 | 0.86 | HTT (0.47) | LTA4HNR1H4 | |
| Trifluoroacetic Acid SCHEMBL20569263 | 0.85 | PDK1 (0.57) | LTA4HPDK1PDK2PDK3PDK4 | |
| SCHEMBL20570012 | 0.82 | S1PR1 (0.53) | NR1H4 | |
| SCHEMBL20572066 | 0.77 | FADS1 (0.44) | — | |
| SCHEMBL20570050 | 0.76 | F10 (0.58) | LTA4HPDK1PDK2PDK3PDK4 | |
| SCHEMBL20570047 | 0.76 | F10 (0.58) | LTA4HPDK1PDK2PDK3PDK4 | |
| SCHEMBL1373113 | 0.76 | MITF (0.51) | LTA4H | |
| SCHEMBL1373110 | 0.76 | MITF (0.51) | LTA4H | |
| SCHEMBL2367781 | 0.74 | IDO1 (0.44) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |