Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20572272 | 0.78 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1PKMKMT2AGAA | |
| SCHEMBL1395967 | 0.77 | TAAR1 (0.63) | L3MBTL1TAAR1ALDH1A1PKMKMT2A | |
| SCHEMBL14696607 | 0.77 | L3MBTL1 (0.53) | L3MBTL1TAAR1ALDH1A1PKMKMT2A | |
| Hydrochloric Acid SCHEMBL19468892 | 0.76 | TAAR1 (0.62) | L3MBTL1TAAR1ALDH1A1PKMKMT2A | |
| SCHEMBL8446165 | 0.76 | L3MBTL1 (0.49) | L3MBTL1TAAR1ALDH1A1PKMKMT2A | |
| SCHEMBL20569330 | 0.76 | HMOX1 (0.40) | — | |
| SCHEMBL20570094 | 0.76 | CYP19A1 (0.44) | — | |
| SCHEMBL19406117 | 0.75 | L3MBTL1 (0.46) | L3MBTL1TAAR1ALDH1A1PKMKMT2A | |
| SCHEMBL28813221 | 0.75 | L3MBTL1 (0.46) | L3MBTL1TAAR1ALDH1A1PKMKMT2A | |
| SCHEMBL4412173 | 0.75 | L3MBTL1 (0.46) | L3MBTL1TAAR1ALDH1A1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |