Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570094 | 0.81 | CYP19A1 (0.44) | IGF1RALOX15CYP19A1KDM5BMCHR1 | |
| Hydrochloric Acid SCHEMBL20570736 | 0.80 | IGF1R (0.38) | IGF1RALOX15CYP19A1KDM5B | |
| SCHEMBL20570469 | 0.77 | PLA2G4A (0.49) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL20569285 | 0.76 | L3MBTL1 (0.57) | — | |
| SCHEMBL20570009 | 0.71 | CYP19A1 (0.71) | HMOX1CYP19A1CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL27032098 | 0.71 | ALPL (0.43) | ALPLPLAAHDAC1ALPG | |
| Hydrochloric Acid SCHEMBL29926046 | 0.69 | ALPL (0.44) | ALPLPLAAHDAC1ALPG | |
| SCHEMBL20569825 | 0.69 | CYP11B1 (0.48) | HMOX1IGF1RALOX15CYP19A1HDAC3 | |
| SCHEMBL5197814 | 0.68 | — | — | |
| SCHEMBL10250244 | 0.67 | HMOX1 (0.72) | HMOX1CYP19A1CYP2A6CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |