Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NEK1 | Q96PY6 | 4/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PTPRG | P23470 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570300 | 0.69 | DAO (0.73) | DAOGPR84 | |
| SCHEMBL20569602 | 0.68 | DAO (0.55) | DAOGPR84CDC7DBF4 | |
| SCHEMBL20569899 | 0.66 | DAO (0.75) | DAOGPR84 | |
| SCHEMBL5241735 | 0.65 | PARP1 (0.42) | NEK1PARP1MEN1KMT2A | |
| SCHEMBL20570332 | 0.63 | DAO (0.52) | DAOGPR84MAPT | |
| SCHEMBL20569900 | 0.62 | GPR84 (0.43) | DAOL3MBTL1GPR84CDC7DBF4 | |
| SCHEMBL27670847 | 0.61 | MAOB (0.46) | RAB9AGPR84CDC7DBF4IDO1 | |
| SCHEMBL24214461 | 0.60 | DAO (1.00) | DAO | |
| SCHEMBL29196577 | 0.60 | KDM4E (0.53) | PARP1KMT2A | |
| SCHEMBL20569629 | 0.59 | DAO (0.71) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |