Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1128289 | 0.85 | KDM4E (0.60) | FABP4FABP5FABP3KDM4EMEN1 | |
| SCHEMBL1128298 | 0.81 | MAPT (0.70) | MEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL1128885 | 0.80 | CYP1A2 (0.52) | FABP4FABP5FABP3KDM4ECYP1A2 | |
| SCHEMBL21426092 | 0.79 | CYP1A2 (0.47) | FABP4FABP5FABP3KDM4ECYP1A2 | |
| SCHEMBL30745333 | 0.79 | CNR2 (0.56) | CYP1A2ALDH1A1CNR1CNR2 | |
| SCHEMBL18014692 | 0.77 | FABP4 (0.51) | FABP4FABP5CYP1A2CYP2C19MEN1 | |
| SCHEMBL9768532 | 0.76 | CYP1A2 (0.70) | FABP4FABP5FABP3KDM4ECYP1A2 | |
| SCHEMBL30904706 | 0.75 | CNR1 (0.53) | CYP1A2MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL31357282 | 0.74 | CNR2 (0.52) | ALDH1A1CNR1CNR2 | |
| SCHEMBL22298166 | 0.73 | PGR (0.49) | FABP4FABP5MAOAACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005730-B2 | 3-aminocarbazole compound, pharmaceutical composition containing it and preparation method therefor | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2018-06-26 | — | — | US | disclosed |
| US-20160102056-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-04-14 | — | — | US | disclosed |
| US-9249097-B2 | 3-aminocarbazole compound, pharmaceutical composition containing it and preparation method therefor | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-02-02 | — | — | US | disclosed |
| US-20140107174-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | AZIENDE CHIM. RIUN. ANG. FRANC. AC.R.A.F. S.p.A. (IT) | 2014-04-17 | — | — | US | disclosed |
| US-8637682-B2 | 3-aminocarbazole compound, pharmaceutical composition containing it and preparation method therefor | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2014-01-28 | — | — | US | disclosed |
| EP-2282994-B1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | ACRAF (IT) | 2013-07-03 | — | — | EP | disclosed |
| US-20110060025-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | AZIENDE CHIM. RIUN.ANG.FRANC. A.C.R.A.F S.p.A. (IT) | 2011-03-10 | — | — | US | disclosed |
| EP-2282994-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. (IT) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009138376-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |
| EP-2119705-A1 | 3-Aminocarbozole compound, pharmaceutical composition containing it and preparation method therefor | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005730-B2 | 3-aminocarbazole compound, pharmaceutical composition containing it and preparation method therefor | PTGES3, PTGER3, PTGES | FABP4 475/4885FABP5 803/4885FABP3 448/4885 |
| US-20160102056-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | PTGES3, PTGER3, PTGES | FABP4 475/4885FABP5 803/4885FABP3 448/4885 |
| US-20140107174-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | PTGES3, PTGER3, PTGES | FABP4 475/4885FABP5 803/4885FABP3 448/4885 |
| US-20110060025-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | PTGES3, PTGER3, PTGES | FABP4 475/4885FABP5 803/4885FABP3 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.