Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 8/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 4/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569812 | 1.00 | TPSAB1 (0.58) | TPSAB1PRSS1PLGCYP1A2CYP2D6 | |
| SCHEMBL20570613 | 0.87 | FNTA (0.49) | TPSAB1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL29968173 | 0.85 | TPSAB1 (0.56) | TPSAB1PRSS1PLGCYP1A2CYP2D6 | |
| SCHEMBL47278 | 0.84 | MMP8 (0.53) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL1697377 | 0.84 | MMP8 (0.53) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL5653978 | 0.84 | MMP8 (0.53) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL18232464 | 0.79 | TPSAB1 (0.61) | TPSAB1PRSS1PLGCYP1A2CYP2D6 | |
| SCHEMBL10070620 | 0.79 | TPSAB1 (0.61) | TPSAB1PRSS1PLGCYP1A2CYP2D6 | |
| SCHEMBL23862447 | 0.76 | BACE1 (0.58) | TPSAB1PRSS1PLGCYP1A2CYP2D6 | |
| SCHEMBL23571643 | 0.76 | TPSAB1 (0.81) | TPSAB1PRSS1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |