Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653978 | 1.00 | MMP8 (0.53) | MMP8KMT2AEGFRSRCCYP1A2 | |
| SCHEMBL1697377 | 1.00 | MMP8 (0.53) | MMP8KMT2AEGFRSRCCYP1A2 | |
| SCHEMBL18952189 | 0.86 | SPHK1 (0.62) | MMP8KMT2AEGFRSRCCYP1A2 | |
| SCHEMBL7413310 | 0.86 | ALPI (0.61) | MMP8KMT2AEGFRSRCMME | |
| SCHEMBL3114367 | 0.86 | ALPI (0.61) | MMP8KMT2AEGFRSRCMME | |
| SCHEMBL12240253 | 0.84 | KMT2A (0.55) | MMP8KMT2AEGFRSRCMME | |
| SCHEMBL2742291 | 0.84 | KMT2A (0.55) | MMP8KMT2AEGFRSRCMME | |
| SCHEMBL20569813 | 0.84 | TPSAB1 (0.58) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL16289699 | 0.84 | MMP2 (0.68) | MMP8KMT2AEGFRSRCCYP1A2 | |
| Hydrochloric Acid SCHEMBL3385081 | 0.84 | MMP8 (0.59) | MMP8KMT2AEGFRSRCMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119335094-A | Reversed-phase liquid chromatography method for detecting lacosamide dry syrup related substances | 海南卫康制药(潜山)有限公司 | 2025-01-21 | — | — | CN | claimed |
| CN-119118860-A | Lacosamide Process for the preparation of amines | 迪嘉药业集团股份有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-106866453-B | A kind of method that microreactor prepares scheme for lacosamide | 齐鲁天和惠世制药有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-106866453-A | A kind of method that microreactor prepares scheme for lacosamide | 齐鲁天和惠世制药有限公司 | 2017-06-20 | — | — | CN | claimed |
| US-8957252-B2 | Process for preparation of lacosamide and some N-benzyl-propanamide intermediate derivatives | INDOCO REMEDIES LIMITED (IN) | 2015-02-17 | — | — | US | claimed |
| US-8829226-B2 | Lacosamide intermediate compound, preparation method thereof and use thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2014-09-09 | — | — | US | claimed |
| EP-2598476-B1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LTD (IN) | 2014-07-02 | — | — | EP | claimed |
| CN-102146048-B | Lacosamide intermediate compound and preparation method and application thereof | ZHEJIANG JIUZHOU PHARM CO LTD | 2013-11-13 | — | — | CN | claimed |
| EP-2598476-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | Indoco Remedies Limited (IN) | 2013-06-05 | — | — | EP | claimed |
| US-20130123522-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LIMITED (IN) | 2013-05-16 | — | — | US | claimed |
| US-20130066102-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2013-03-14 | — | — | US | claimed |
| US-20130041180-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2013-02-14 | — | — | US | claimed |
| EP-2534127-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN Laboratories Limited (IN) | 2012-12-19 | — | — | EP | claimed |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2012-11-08 | — | — | US | claimed |
| WO-2012014226-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2011099033-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-08-18 | — | — | WO | claimed |
| CN-102146048-A | Lacosamide intermediate compound and preparation method and application thereof | ZHEJIANG JIUZHOU PHARM CO LTD | 2011-08-10 | — | — | CN | claimed |
| CN-119335094-A | Reversed-phase liquid chromatography method for detecting lacosamide dry syrup related substances | 海南卫康制药(潜山)有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-102146048-A | Lacosamide intermediate compound and preparation method and application thereof | ZHEJIANG JIUZHOU PHARM CO LTD | 2011-08-10 | — | — | CN | disclosed |
| WO-2011039781-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066102-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | IDH3A, CACNA1C, DDC | MMP8 778/4885KMT2A 723/4885EGFR 2617/4885 |
| US-20130123522-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | LPXN, CACNA1B, PMP22 | MMP8 3706/4885KMT2A 792/4885EGFR 3135/4885 |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | IDH3A, CACNA1C, DDC | MMP8 778/4885KMT2A 723/4885EGFR 2617/4885 |
| US-20130041180-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | AMY1A, PTMA, NAAA | MMP8 4364/4885KMT2A 1675/4885EGFR 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.