Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665393 | 0.84 | LMNA (0.40) | KDM4EMAPK1NPC1RAB9AMAPT | |
| SCHEMBL5922464 | 0.84 | ALDH1A1 (0.47) | KDM4ERAB9AMAPTALDH1A1LMNA | |
| SCHEMBL2474079 | 0.80 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1284438 | 0.77 | MAOB (0.45) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL23036465 | 0.77 | LMNA (0.34) | KDM4EMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4748690 | 0.75 | NR5A1 (0.51) | MAPT | |
| SCHEMBL7210942 | 0.75 | NR5A1 (0.51) | MAPT | |
| SCHEMBL4749149 | 0.75 | NR5A1 (0.51) | MAPT | |
| SCHEMBL4745433 | 0.75 | NR5A1 (0.51) | MAPT | |
| SCHEMBL9699146 | 0.75 | NR5A1 (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |