Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 16/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234711 | 0.90 | FAAH (0.69) | FAAHLMNAS1PR5ALDH1A1 | |
| SCHEMBL3355088 | 0.86 | FAAH (0.74) | FAAHLMNAALDH1A1 | |
| SCHEMBL20567770 | 0.84 | FAAH (0.58) | FAAHLMNAALDH1A1 | |
| SCHEMBL2932454 | 0.82 | L3MBTL1 (0.54) | FAAHLMNAALDH1A1 | |
| SCHEMBL20566600 | 0.81 | FAAH (1.00) | FAAH | |
| SCHEMBL30302097 | 0.81 | FAAH (1.00) | FAAH | |
| SCHEMBL2931705 | 0.81 | AKR1C3 (0.65) | FAAHLMNAALDH1A1 | |
| SCHEMBL5471849 | 0.80 | FAAH (0.71) | FAAHLMNAALDH1A1 | |
| SCHEMBL24971338 | 0.80 | FAAH (0.78) | FAAH | |
| SCHEMBL20567009 | 0.79 | LTA4H (0.52) | FAAHLMNAS1PR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-A1 | PYRAZOLE MAGL INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018217805-A1 | PYRAZOLE MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-11-29 | — | — | WO | disclosed |